ARG43637
anti-RAET1E / ULBP4 antibody
anti-RAET1E / ULBP4 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RAET1E / ULBP4 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RAET1E / ULBP4 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within a.a 150-180 of Human RAET1E / ULBP4 protein. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Retinoic acid early transcript 1E |
| 別名 | LETAL; Retinoic acid early transcript 1E; RAE-1-like transcript 4; bA350J20.7; N2DL-4; NKG2DL4; ULBP4; RAET1E2; RL-4; Lymphocyte effector toxicity activation ligand; NKG2D ligand 4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | ~ 30-35 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% Sodium azide. |
| 抗菌剂 | 0.09% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RAET1E |
| 全名 | retinoic acid early transcript 1E |
| 背景介绍 | This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011] |
| 生物功能 | Ligand for the KLRK1 receptor. Delivers activating signals to NK cells and promotes tumor immune surveillance by inducing the expansion of anti-tumor cytotoxic lymphocytes. [UniProt] |
| 细胞定位 | Membrane; Secreted |
| 预测分子量 | 30 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein |
