ARG43877
anti-RAB43 antibody
anti-RAB43 antibody for ELISA,Flow cytometry,ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RAB43 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RAB43 |
| 抗原物种 | Human |
| 抗原 | Human RAB43 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Ras-related protein Rab-43 |
| 別名 | RAB43; RAB43; Member RAS Oncogene Family; RAB41; RAB11B; Ras-Related Protein Rab-43; Ras-Related Protein Rab-41; ISY1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RAB43 |
| 全名 | RAB43, Member RAS Oncogene Family |
| 生物功能 | Enables GTPase activity. Involved in several processes, including Golgi organization; phagosome maturation; and retrograde transport, plasma membrane to Golgi. Located in Golgi apparatus and phagocytic vesicle. |
| 细胞定位 | Cytoplasmic vesicle, Golgi apparatus, Membrane |
| 产品亮点 | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. |
| 预测分子量 | 23 kDa |
| 翻译后修饰 | Lipoprotein, Methylation, Phosphoprotein, Prenylation |
检测图片 (3) Click the Picture to Zoom In
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ARG43877 anti-RAB43 antibody ICC/IF image
Immunofluorescence: MCF-7 cells stained with ARG43877 anti-RAB43 antibody at 1:500 dilution.
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ARG43877 anti-RAB43 antibody WB image
Western blot: HepG2 stained with ARG43877 anti-RAB43 antibody at 1:5000 dilution.
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ARG43877 anti-RAB43 antibody FACS image
Flow Cytometry: HL-60 cells stained with ARG43877 anti-RAB43 antibody (blue) at 1 μg/1x10^6 cells dilution.
