ARG55740
anti-RAB27A antibody
anti-RAB27A antibody for ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Dog,Monkey
概述
| 产品描述 | Goat Polyclonal antibody recognizes RAB27A |
|---|---|
| 反应物种 | Hu, Ms, Rat, Dog, Mk |
| 应用 | ICC/IF, IHC-Fr, IHC-P, WB |
| 特异性 | Detects Rab27a by Western blot in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab27a. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RAB27A |
| 抗原物种 | Mouse |
| 抗原 | Purified recombinant peptide around aa. 120 (C-terminus) of Mouse Rab27a |
| 偶联标记 | Un-conjugated |
| 別名 | ash; Ras-related protein Rab-27A |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen retrieval: Heat-induced. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.05% Sodium azide and 20% Glycerol |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 20% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Rab27a |
| 全名 | RAB27A, member RAS oncogene family |
| 背景介绍 | The protein encoded by this gene is a member of the Rab family of proteins, which is the largest family within the Ras superfamily of GTPases. This gene product is thought to regulate vesicular transport, together with its specific effectors. Mutations in this gene cause several defects, including actin-based melanosome transport defects and immunodeficiency. Mutations in the human ortholog of this gene are associated with Griscelli syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| 生物功能 | Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse (By similarity). [UniProt] |
| 预测分子量 | 25 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG55740 anti-RAB27A antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded albino mouse retina stained with ARG55740 anti-RAB27A antibody at 1:200 dilution. Antigen retrieval: Heat-induced.
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ARG55740 anti-RAB27A antibody WB image
Western blot: 1) AtT-20, 2) Melan-ink, 3) ARPE19, 4) ARPE19 + miRNA neg, 5) ARPE19 + miRNA1, 6) ARPE19 + miRNA2, and 7) ARPE19 + miRNA3 stained with ARG55740 anti-RAB27A antibody at 1:500 dilution.
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ARG55740 anti-RAB27A antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded mammary tissue stained with ARG55740 anti-RAB27A antibody at 1:200 dilution. Antigen retrieval: Heat-induced.
