概述

产品描述	Rabbit Polyclonal antibody recognizes QPCT
反应物种	Hu, Ms, Rat
应用	ICC/IF, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	QPCT
抗原物种	Human
抗原	Recombinant fusion protein corresponding to aa. 1-361 of Human QPCT (NP_036545.1).
偶联标记	Un-conjugated
別名	EC 2.3.2.5; Glutaminyl cyclase; Glutamyl cyclase; EC; QC; Glutaminyl-peptide cyclotransferase; GCT; sQC; Glutaminyl-tRNA cyclotransferase

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:50 - 1:200 WB 1:1000 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 25797 Human QPCT GeneID: 70536 Mouse QPCT Swiss-port # Q16769 Human Glutaminyl-peptide cyclotransferase Swiss-port # Q9CYK2 Mouse Glutaminyl-peptide cyclotransferase
基因名称	QPCT
全名	glutaminyl-peptide cyclotransferase
背景介绍	This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008]
生物功能	Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-amyloid-beta. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides. [UniProt]
细胞定位	Secreted. [UniProt]
预测分子量	41 kDa

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