ARG64022
anti-QKI / Quaking antibody
anti-QKI / Quaking antibody for Western blot and Mouse
Gene Regulation antibody; Neuroscience antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes QKI / Quaking |
|---|---|
| 反应物种 | Ms |
| 预测物种 | Hu, Rat, Cow, Dog, Pig |
| 应用 | WB |
| 特异性 | This antibody is expected to recognise all reported isoforms (NP_006766.1; NP_996735.1; NP_996736.1; NP_996737.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | QKI / Quaking |
| 抗原物种 | Human |
| 抗原 | ETKEKPKPTPDY-C |
| 偶联标记 | Un-conjugated |
| 別名 | hqkI; HqkI; Hqk; QK3; QK; Protein quaking; QK1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 背景介绍 | The protein encoded by this gene is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. The encoded protein is involved in myelinization and oligodendrocyte differentiation and may play a role in schizophrenia. Four transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2011] |
|---|---|
| 研究领域 | Gene Regulation antibody; Neuroscience antibody |
| 预测分子量 | 38 kDa |
| 翻译后修饰 | Methylated by PRMT1. Tyrosine phosphorylated at its C-terminus, probably by FYN. Phosphorylation leads to decreased mRNA-binding affinity, affecting transport and/or stabilization of MBP mRNA (By similarity). |
检测图片 (1) Click the Picture to Zoom In
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ARG64022 anti-QKI / Quaking antibody WB image
Western blot: Mouse brain lysate (35 µg protein in RIPA buffer) stained with ARG64022 anti-QKI / Quaking antibody at 0.3 µg/ml dilution.
