ARG43984
anti-Prostasin antibody
anti-Prostasin antibody for ELISA,Flow cytometry,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Prostasin |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Prostasin |
| 抗原物种 | Human |
| 抗原 | Human Prostasin recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Prostasin |
| 別名 | PRSS8; Serine Protease 8; CAP1; Prostasin; Channel-Activating Serine Protease 1; Channel-Activating Protease 1; Protease, Serine 8; EC 3.4.21.120; EC 3.4.21.- ; PROSTASIN; EC 3.4.21 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRSS8 |
| 全名 | Serine Protease 8 |
| 背景介绍 | This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation. |
| 生物功能 | Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits. |
| 细胞定位 | Cell membrane, Membrane, Secreted |
| 预测分子量 | 36 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Zymogen |
检测图片 (2) Click the Picture to Zoom In
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ARG43984 anti-Prostasin antibody WB image
Western blot: Caco-2 and MCF-7 stained with ARG43984 anti-Prostasin antibody at 0.5 μg/mL dilution.
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ARG43984 anti-Prostasin antibody FACS image
Flow Cytometry: MCF-7 cells stained with ARG43984 anti-Prostasin antibody (blue) at 1 μg/1x10^6 cells dilution.
