ARG56504
anti-Prostaglandin I Synthase antibody [isn-1]
anti-Prostaglandin I Synthase antibody [isn-1] for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation and Mouse,Rat,Bovine,Guinea pig,Rabbit,Sheep
概述
| 产品描述 | Mouse Monoclonal antibody [isn-1] recognizes Prostaglandin I Synthase |
|---|---|
| 反应物种 | Ms, Rat, Bov, Gpig, Rb, Sheep |
| 应用 | ICC/IF, IHC-P, IP |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | isn-1 |
| 同位型 | IgG1 |
| 靶点名称 | Prostaglandin I Synthase |
| 抗原物种 | Bovine |
| 抗原 | Bovine lung Prostaglandin I Synthase. |
| 偶联标记 | Un-conjugated |
| 別名 | PTGI; CYP8A1; Prostaglandin I2 synthase; EC 5.3.99.4; PGIS; Prostacyclin synthase; CYP8 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | TBS (pH 7.4) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PTGIS |
| 全名 | prostaglandin I2 (prostacyclin) synthase |
| 背景介绍 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008] |
| 生物功能 | Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2). [UniProt] |
| 预测分子量 | 57 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG56504 anti-Prostaglandin I Synthase antibody [isn-1] ICC/IF image
Immunocytochemistry: Bovine CPAE cells stained with ARG56504 anti-Prostaglandin I Synthase antibody [isn-1] (red) at 15 µg/ml dilution.
