ARG56466

anti-Prostaglandin E Synthase (cytosolic, FL) antibody

anti-Prostaglandin E Synthase (cytosolic, FL) antibody for ICC/IF,Western blot and Human,Mouse

概述

产品描述 Rabbit Polyclonal antibody recognizes Prostaglandin E Synthase (cytosolic, FL)
反应物种 Hu, Ms
应用 ICC/IF, WB
特异性 This antibody does not react to Microsomal PGES-1 and Microsomal PGES-2.
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 Prostaglandin E Synthase (cytosolic, FL)
抗原物种 Human
抗原 Full length, Human recombinant Prostaglandin E Synthase (cytosolic, FL).
偶联标记 Un-conjugated
別名 EC 5.3.99.3; Progesterone receptor complex p23; TEBP; Hsp90 co-chaperone; P23; cPGES; Cytosolic prostaglandin E2 synthase; Prostaglandin E synthase 3; Telomerase-binding protein p23

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:20 (10 µg/ml)
WB1:200 (1 µg/ml)
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 10728 Human PTGES3

GeneID: 56351 Mouse PTGES3

Swiss-port # Q15185 Human Prostaglandin E synthase 3

Swiss-port # Q9R0Q7 Mouse Prostaglandin E synthase 3

基因名称 PTGES3
全名 prostaglandin E synthase 3 (cytosolic)
生物功能 Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. [UniProt]
预测分子量 19 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG56466 anti-Prostaglandin E Synthase (cytosolic, FL) antibody WB image

    Western blot: 1) 0.01 µg of Recombinant p23 protein (pure), and 2) 0.02 µg of Recombinant p23 protein (pure) stained with ARG56466 anti-Prostaglandin E Synthase (cytosolic, FL) antibody.