ARG55645
anti-Prohibitin phospho (Tyr259) antibody
anti-Prohibitin phospho (Tyr259) antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Prohibitin phospho (Tyr259) |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 特异性 | The antibody detects endogenous level of Prohibitin only when phosphorylated at tyrosine 259. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Prohibitin |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated phosphospecific peptide around Tyr259 (I-T-Y(p)-L-P) derived from Human Prohibitin. |
| 偶联标记 | Un-conjugated |
| 別名 | HEL-215; PHB1; Prohibitin; HEL-S-54e |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with phospho-specific peptide and the non-phospho specific antibodies were removed by chromatography using non-phosphopeptide. |
| 缓冲液 | PBS (pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PHB |
| 全名 | prohibitin |
| 背景介绍 | This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| 生物功能 | Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging. [UniProt] |
| 预测分子量 | 30 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG55645 anti-Prohibitin phospho (Tyr259) antibody WB image
Western blot: MCF, PC12, 293 and 3T3 cell lysates stained with ARG55645 anti-Prohibitin phospho (Tyr259) antibody.
