ARG55648

anti-Prohibitin antibody

anti-Prohibitin antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes Prohibitin
反应物种 Hu, Ms, Rat
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 Prohibitin
抗原物种 Human
抗原 Recombinant protein of Human Prohibitin.
偶联标记 Un-conjugated
別名 HEL-215; PHB1; Prohibitin; HEL-S-54e

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 PC-12 and PC-3
实际分子量 ~ 30 kDa

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 18673 Mouse PHB

GeneID: 25344 Rat PHB

GeneID: 5245 Human PHB

基因名称 PHB
全名 prohibitin
背景介绍 This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
生物功能 Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging. [UniProt]
预测分子量 30 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG55648 anti-Prohibitin antibody ICC/IF image

    Immunofluorescence: HeLa cells stained with ARG55648 anti-Prohibitin antibody.

  • ARG55648 anti-Prohibitin antibody WB image

    Western blot: PC-12 and PC-3 cell lysates stained with ARG55648 anti-Prohibitin antibody.