ARG64376
anti-Proenkephalin antibody
anti-Proenkephalin antibody for IHC-Frozen sections,Western blot and Human
Neuroscience antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes Proenkephalin |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-Fr, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Proenkephalin |
| 抗原物种 | Human |
| 抗原 | C-RSHHQDGSDNEE |
| 偶联标记 | Un-conjugated |
| 別名 | 143-183; PENK-A; PE; 114-133; Proenkephalin-A; 237-258; OGF; Opioid growth factor |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PENK |
| 全名 | proenkephalin |
| 背景介绍 | This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the pentapeptide opioids Met-enkephalin and Leu-enkephalin, which are stored in synaptic vesicles, then released into the synapse where they bind to mu- and delta-opioid receptors to modulate the perception of pain. Other non-opioid cleavage products may function in distinct biological activities. [provided by RefSeq, Jul 2015] |
| 生物功能 | Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum. [UniProt] |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 31 kDa |
| 翻译后修饰 | The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing. |
检测图片 (2) Click the Picture to Zoom In
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ARG64376 anti-Proenkephalin antibody WB image
Western Blot: Human Adrenal Gland lysate (35 µg protein in RIPA buffer) stained with ARG64376 anti-Proenkephalin antibody at 0.3 µg/ml dilution.
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ARG64376 anti-Proenkephalin antibody IHC-Fr image
Immunohistochemistry: PFA-perfused cryosection of Human hypothalamus tissue stained with ARG64376 anti-Proenkephalin antibody at 0.3 µg/ml dilution.
