ARG58128
anti-Pleiotrophin antibody
anti-Pleiotrophin antibody for IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Pleiotrophin |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Pleiotrophin |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the C-terminus of Human Pleiotrophin (QAESKKKKKEGKKQEKMLD). (100% homologous in Human, Mouse and Rat). |
| 偶联标记 | Un-conjugated |
| 別名 | PTN; HBNF; Heparin-binding growth-associated molecule; Heparin-binding neurite outgrowth-promoting factor 1; HBGF8; HBNF-1; HBBM; Pleiotrophin; HBGF-8; OSF-1; Osteoblast-specific factor 1; Heparin-binding growth factor 8; Heparin-binding brain mitogen; NEGF1; HB-GAM; HARP |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.025% Sodium azide and 2.5% BSA. |
| 抗菌剂 | 0.025% Sodium azide |
| 稳定剂 | 2.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PTN |
| 全名 | pleiotrophin |
| 生物功能 | Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. [UniProt] |
| 细胞定位 | Cytoplasmic, membranous. [UniProt] |
| 预测分子量 | 19 kDa |
| 翻译后修饰 | Phosphorylated by NEK6. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
-
ARG58128 anti-Pleiotrophin antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human breast cancer tissue stained with ARG58128 anti-Pleiotrophin antibody.
