ARG56498
anti-Phospholipase A2 IIA antibody [SCACC353]
anti-Phospholipase A2 IIA antibody [SCACC353] for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [SCACC353] recognizes Phospholipase A2 IIA |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, IP, WB |
| 特异性 | This antibody does not react to Human sPLA2 (Type V). |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | SCACC353 |
| 同位型 | IgG1 |
| 靶点名称 | Phospholipase A2 IIA |
| 抗原物种 | Human |
| 抗原 | Human recombinant synovial Phospholipase A2 IIA. |
| 偶联标记 | Un-conjugated |
| 別名 | PLA2B; GIIC sPLA2; EC 3.1.1.4; Non-pancreatic secretory phospholipase A2; PLA2; MOM1; PLA2L; PLAS1; PLA2S; NPS-PLA2; Group IIA phospholipase A2; sPLA2; Phospholipase A2, membrane associated; Phosphatidylcholine 2-acylhydrolase 2A |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2), 0.02% Sodium azide, 50% Glycerol and 0.1% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.1% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P14555 Human Phospholipase A2, membrane associated |
|---|---|
| 基因名称 | PLA2G2A |
| 全名 | phospholipase A2, group IIA (platelets, synovial fluid) |
| 背景介绍 | The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009] |
| 生物功能 | Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. [UniProt] |
| 预测分子量 | 16 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG56498 anti-Phospholipase A2 IIA antibody [SCACC353] WB image
Western blot: 1) 250ng of Human sPLA2 type II stained with ARG56498 anti-Phospholipase A2 IIA antibody [SCACC353].
