ARG59476
anti-Peroxiredoxin 2 antibody
anti-Peroxiredoxin 2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Peroxiredoxin 2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Peroxiredoxin 2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human Peroxiredoxin 2. |
| 偶联标记 | Un-conjugated |
| 別名 | EC 1.11.1.15; TPX1; TDPX1; HEL-S-2a; PTX1; Thiol-specific antioxidant protein; PRX2; TSA; Peroxiredoxin-2; PRP; Thioredoxin-dependent peroxide reductase 1; NKEF-B; NKEFB; Natural killer cell-enhancing factor B; Thioredoxin peroxidase 1; PRXII |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 阳性对照 | HEK293 | ||||||||||
| 实际分子量 | ~ 22 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRDX2 |
| 全名 | peroxiredoxin 2 |
| 背景介绍 | This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013] |
| 生物功能 | Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 22 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59476 anti-Peroxiredoxin 2 antibody WB image
Western blot: HEK293 cell lysate stained with ARG59476 anti-Peroxiredoxin 2 antibody.
