ARG66175
anti-Peroxiredoxin 1 antibody
anti-Peroxiredoxin 1 antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Mouse Monoclonal antibody recognizes Peroxiredoxin 1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 特异性 | The antibody detects endogenous Peroxiredoxin 1 protein. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 靶点名称 | Peroxiredoxin 1 |
| 抗原物种 | Human |
| 抗原 | Recombinant Protein of Human Peroxiredoxin 1. |
| 偶联标记 | Un-conjugated |
| 別名 | EC 1.11.1.15; TDPX2; PAG; PRX1; MSP23; Natural killer cell-enhancing factor A; Peroxiredoxin-1; PRXI; NKEFA; PAGA; PAGB; Proliferation-associated gene protein; Thioredoxin peroxidase 2; NKEF-A; Thioredoxin-dependent peroxide reductase 2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRDX1 |
| 全名 | peroxiredoxin 1 |
| 背景介绍 | This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011] |
| 生物功能 | Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity). [UniProt] |
| 预测分子量 | 22 kDa |
| 翻译后修饰 | Phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity. |
检测图片 (2) Click the Picture to Zoom In
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ARG66175 anti-Peroxiredoxin 1 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG66175 anti-Peroxiredoxin 1 antibody (green).
Left: Target. Middle: DAPI. Right: merge image.
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ARG66175 anti-Peroxiredoxin 1 antibody WB image
Western blot: 1) MCF7, 2) Rat kidney, and 3) Mouse brain lysates stained with ARG66175 anti-Peroxiredoxin 1 antibody at 1:2000 dilution.
