ARG67099
anti-Perilipin 1 antibody
anti-Perilipin 1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Perilipin 1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Perilipin 1 |
| 抗原 | Synthetic peptide |
| 偶联标记 | Un-conjugated |
| 別名 | Perilipin-1; PERI; Lipid droplet-associated protein; PLIN; FPLD4 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~ 68 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 100 mM Tris Glycine (pH 7.0), 0.025% ProClin 300, 20% Glycerol and 1% BSA. |
| 抗菌剂 | 0.025% ProClin 300 |
| 稳定剂 | 20% Glycerol and 1% BSA |
| 浓度 | 1.26 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PLIN1 |
| 全名 | perilipin 1 |
| 背景介绍 | The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Feb 2009] |
| 生物功能 | Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels. [UniProt] |
| 细胞定位 | Endoplasmic reticulum. Lipid droplet. Note=Lipid droplet surface-associated. [UniProt] |
| 预测分子量 | 56 kDa |
| 翻译后修饰 | Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet (By similarity). [UniProt] |
检测图片 (4) Click the Picture to Zoom In
-
ARG67099 anti-Perilipin 1 antibody IHC-P image
Immunohistochemistry: Human cancer stained with ARG67099 anti-Perilipin 1 antibody at 1:100 dilution.
-
ARG67099 anti-Perilipin 1 antibody WB image
Western blot: Human adipose stained with ARG67099 anti-Perilipin 1 antibody at 1: 1500 dilution.
-
ARG67099 anti-Perilipin 1 antibody IHC-P image
Immunohistochemistry: Mouse adipose stained with ARG67099 anti-Perilipin 1 antibody at 1:200 dilution.
-
ARG67099 anti-Perilipin 1 antibody WB image
Western blot: Mouse adipose stained with ARG67099 anti-Perilipin 1 antibody at 1: 1500 dilution.
