ARG45162

anti-PYROXD1 antibody

anti-PYROXD1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes PYROXD1
反应物种 Hu, Ms, Rat
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 PYROXD1
抗原物种 Human
抗原 Recombinant protein containing to human PYROXD1.
偶联标记 Un-conjugated
別名 PYROXD1; pyridine nucleotide-disulphide oxidoreductase domain 1; Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; PYROXD1

应用说明

应用建议
应用 推荐稀释比
IHC-P0.5-1 μg/ml
WB0.1-0.5 μg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 50-56 kDa

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose.
抗菌剂 0.05% Sodium azide
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 232491 Mouse PYROXD1

GeneID: 297708 Rat PYROXD1

GeneID: 79912 Human PYROXD1

基因名称 PYROXD1
全名 pyridine nucleotide-disulphide oxidoreductase domain 1
背景介绍 This gene encodes a nuclear-cytoplasmic pyridine nucleotide-disulphide reductase (PNDR). PNDRs are flavoproteins that catalyze the pyridine nucleotide-dependent reduction of thiol residues in other proteins. The encoded protein belongs to the class I pyridine nucleotide-disulphide oxidoreductase family but lacks the C-terminal dimerization domain found in other family members and instead has a C-terminal nitrile reductase domain. It localizes to the nucleus and to striated sarcomeric compartments. Naturally occurring mutations in this gene cause early-onset myopathy with internalized nuclei and myofibrillar disorganization. A pseudogene of this gene has been defined on chromosome 11. [provided by RefSeq, Apr 2017]
生物功能 Probable FAD-dependent oxidoreductase; involved in the cellular oxidative stress response. [UniProt]
细胞定位 Nucleus; Cytoplasm. [UniProt]
预测分子量 56 kDa
翻译后修饰 Probable FAD-dependent oxidoreductase; involved in the cellular oxidative stress response. [UniProt]

检测图片 (5) Click the Picture to Zoom In

  • ARG45161 anti-PPA2 antibody IHC-P image

    Immunohistochemistry: Human mammary cancer stained with ARG45161 anti-PPA2 antibody at 1 μg/ml dilution.

  • ARG45162 anti-PYROXD1 antibody WB image

    Western blot: Human placenta, U-87MG, HL-60, THP-1, and PC-3 stained with ARG45162 anti-PYROXD1 antibody at 0.5 μg/ml dilution.

  • ARG45162 anti-PYROXD1 antibody IHC-P image

    Immunohistochemistry: Rat intestine stained with ARG45162 anti-PYROXD1 antibody at 1 μg/ml dilution.

  • ARG45162 anti-PYROXD1 antibody WB image

    Western blot: Rat kidney stained with ARG45162 anti-PYROXD1 antibody at 0.5 μg/ml dilution.

  • ARG45161 anti-PPA2 antibody IHC-P image

    Immunohistochemistry: Mouse intestine stained with ARG45161 anti-PPA2 antibody at 1 μg/ml dilution.