ARG44391
anti-PXYLP1 antibody
anti-PXYLP1 antibody for Flow cytometry,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PXYLP1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PXYLP1 |
| 抗原物种 | Human |
| 抗原 | Human PXYLP1 recombinant protein (aa. sequence: K45-D459). |
| 偶联标记 | Un-conjugated |
| 別名 | PXYLP1; 2-Phosphoxylose Phosphatase 1; ACPL2; Acid Phosphatase-Like Protein 2; Epididymis Luminal Protein 124; Acid Phosphatase-Like 2; Xylosyl Phosphatase |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PXYLP1 |
| 全名 | 2-Phosphoxylose Phosphatase 1 |
| 背景介绍 | Enables phosphatase activity. Involved in chondroitin sulfate proteoglycan biosynthetic process; glycosaminoglycan biosynthetic process; and positive regulation of heparan sulfate proteoglycan biosynthetic process. Located in Golgi apparatus. |
| 生物功能 | Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains. |
| 细胞定位 | Golgi apparatus, Membrane |
| 预测分子量 | 55 kDa |
| 翻译后修饰 | Glycoprotein |
检测图片 (4) Click the Picture to Zoom In
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ARG44391 anti-PXYLP1 antibody WB image
Western blot: Jurkat and RT4 stained with ARG44391 anti-PXYLP1 antibody at 0.5 μg/mL dilution.
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ARG44391 anti-PXYLP1 antibody FACS image
Flow Cytometry: SH-SY5Y stained with ARG44391 anti-PXYLP1 antibody at 1, 1 μg/10^6 cells dilution.
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ARG44391 anti-PXYLP1 antibody WB image
Western blot: Rat liver stained with ARG44391 anti-PXYLP1 antibody at 0.5 μg/mL dilution.
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ARG44391 anti-PXYLP1 antibody WB image
Western blot: Mouse liver stained with ARG44391 anti-PXYLP1 antibody at 0.5 μg/mL dilution.
