ARG63161
anti-PTP4A1 / PRL1 antibody
anti-PTP4A1 / PRL1 antibody for Western blot and Human
Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes PTP4A1 / PRL1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Dog |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PTP4A1 / PRL1 |
| 抗原物种 | Human |
| 抗原 | KDSNGHRNNCCIQ |
| 偶联标记 | Un-conjugated |
| 別名 | HH72; PTPCAAX1; Protein tyrosine phosphatase type IVA 1; PTP(CAAX1); PRL1; PRL-1; CAAXI; Protein-tyrosine phosphatase of regenerating liver 1; Protein-tyrosine phosphatase 4a1; EC 3.1.3.48; PTP |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q93096 Human Protein tyrosine phosphatase type IVA 1 |
|---|---|
| 背景介绍 | The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq, Jul 2008] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 20 kDa |
| 翻译后修饰 | Farnesylated. Farnesylation is required for membrane targeting. Unfarnesylated forms are shifted into the nucleus. |
检测图片 (1) Click the Picture to Zoom In
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ARG63161 anti-PTP4A1 / PRL1 antibody WB image
Western blot: A549 lysate (35 µg protein in RIPA buffer) stained with ARG63161 anti-PTP4A1 / PRL1 antibody at 1 µg/ml dilution.
