ARG62588
anti-PTHR1 antibody [3D1.1]
anti-PTHR1 antibody [3D1.1] for Immunohistochemistry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Mouse Monoclonal antibody [3D1.1] recognizes PTHR1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 3D1.1 |
| 同位型 | IgG1, kappa |
| 靶点名称 | PTHR1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to amino acids 146-169 of the human PTH/PTHrP receptor (RRCDRNGSWELVPGHNRTWANYSE). |
| 偶联标记 | Un-conjugated |
| 別名 | Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; Parathyroid hormone 1 receptor; PTHR1; PTH/PTHr receptor; PFE; PTHR; PTH1 receptor |
应用说明
| 应用说明 | WB: 0.5-2 ug/ml IHC: 1/10 - 1/500 IHC-P: 5 ug/ml * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G purified |
| 缓冲液 | 1X PBS buffer with < 0.1% sodium azide. |
| 抗菌剂 | < 0.1% sodium azide. |
| 浓度 | 2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q03431 Human Parathyroid hormone/parathyroid hormone-related peptide receptor |
|---|---|
| 基因名称 | PTH1R |
| 全名 | parathyroid hormone 1 receptor |
| 背景介绍 | The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010] |
| 生物功能 | This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. [UniProt] |
| 研究领域 | Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 66 kDa |
克隆号文献
The effects of PTH, loading and surgical insult on cancellous bone at the bone-implant interface in the rabbit.
IHC-P / Rabbit
Expression of parathyroid-hormone- related protein in the partially obstructed rabbit bladder.
IHC-P / Rabbit
Expression and specific immunolocalization of the human parathyroid hormone/parathyroid hormone-related protein receptor in the uteroplacental unit.
