ARG44002
anti-PSMF1 antibody
anti-PSMF1 antibody for ELISA,Flow cytometry,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PSMF1 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PSMF1 |
| 抗原物种 | Human |
| 抗原 | Human PSMF1 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Proteasome inhibitor PI31 subunit |
| 別名 | PSMF1; Proteasome Inhibitor Subunit 1; PI31; Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31); Proteasome Inhibitor PI31 Subunit; Proteasome Inhibitor HP131 Subunit; HPI31 |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PSMF1 |
| 全名 | Proteasome Inhibitor Subunit 1 |
| 背景介绍 | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene. |
| 生物功能 | Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28. |
| 细胞定位 | Cytoplasm, Endoplasmic reticulum, Proteasome |
| 预测分子量 | 30 kDa |
| 翻译后修饰 | Acetylation, Methylation, Phosphoprotein |
检测图片 (2) Click the Picture to Zoom In
-
ARG44002 anti-PSMF1 antibody WB image
Western blot: Jurkat and HepG2 stained with ARG44002 anti-PSMF1 antibody at 0.5 μg/mL dilution.
-
ARG44002 anti-PSMF1 antibody FACS image
Flow Cytometry: JK cells stained with ARG44002 anti-PSMF1 antibody (blue) at 1 μg/1x10^6 cells dilution.
