ARG41039
anti-PSMD8 antibody
anti-PSMD8 antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PSMD8 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PSMD8 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 101-350 of Human PSMD8 (NP_002803.2). |
| 偶联标记 | Un-conjugated |
| 別名 | HEL-S-91n; p31; HIP6; S14; 26S proteasome regulatory subunit S14; 26S proteasome non-ATPase regulatory subunit 8; 26S proteasome regulatory subunit RPN12; Rpn12; Nin1p; HYPF |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse skeletal muscle | ||||||
| 实际分子量 | 35 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P48556 Human 26S proteasome non-ATPase regulatory subunit 8 Swiss-port # Q9CX56 Mouse 26S proteasome non-ATPase regulatory subunit 8 |
|---|---|
| 基因名称 | PSMD8 |
| 全名 | proteasome 26S subunit, non-ATPase 8 |
| 背景介绍 | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008] |
| 生物功能 | Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase. [UniProt] |
| 预测分子量 | 40 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG41039 anti-PSMD8 antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG41039 anti-PSMD8 antibody.
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ARG41039 anti-PSMD8 antibody WB image
Western blot: 25 µg of Mouse skeletal muscle lysate stained with ARG41039 anti-PSMD8 antibody at 1:1000 dilution.
