概述

产品描述	Rabbit Polyclonal antibody recognizes PSMD14
反应物种	Hu, Ms, Rat
应用	ICC/IF, IHC-P, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	PSMD14
抗原物种	Human
抗原	Synthetic peptide of Human PSMD14.
偶联标记	Un-conjugated
別名	RPN11; 26S proteasome non-ATPase regulatory subunit 14; 26S proteasome-associated PAD1 homolog 1; POH1; PAD1; EC 3.4.19.-; 26S proteasome regulatory subunit RPN11

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:50 - 1:200 IHC-P 1:50 - 1:200 WB 1:1000 - 1:5000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量	~ 35 kDa

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂	0.01% Sodium azide
稳定剂	40% Glycerol and 0.05% BSA
浓度	Batch dependent
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 10213 Human PSMD14 GeneID: 59029 Mouse PSMD14 Swiss-port # O00487 Human 26S proteasome non-ATPase regulatory subunit 14 Swiss-port # O35593 Mouse 26S proteasome non-ATPase regulatory subunit 14
基因名称	PSMD14
全名	proteasome 26S subunit, non-ATPase 14
背景介绍	This gene encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on the long arm of chromosome 2. [provided by RefSeq, Feb 2012]
生物功能	Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. Plays a role in response to double-strand breaks (DSBs): acts as a regulator of non-homologous end joining (NHEJ) by cleaving 'Lys-63'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. Also involved in homologous recombination repair by promoting RAD51 loading. [UniProt]
预测分子量	35 kDa

检测图片 (1) Click the Picture to Zoom In