ARG56225
anti-PSMD13 antibody
anti-PSMD13 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PSMD13 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Chk |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PSMD13 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 269-298 (C-terminal) of HHuman PSMD13. |
| 偶联标记 | Un-conjugated |
| 別名 | 26S proteasome regulatory subunit RPN9; HSPC027; 26S proteasome non-ATPase regulatory subunit 13; Rpn9; S11; 26S proteasome regulatory subunit S11; 26S proteasome regulatory subunit p40.5; p40.5 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Y79 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9UNM6 Human 26S proteasome non-ATPase regulatory subunit 13 |
|---|---|
| 基因名称 | PSMD13 |
| 全名 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 |
| 背景介绍 | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| 生物功能 | Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. [UniProt] |
| 预测分子量 | 43 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG56225 anti-PSMD13 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human lung carcinoma tissue stained with ARG56225 anti-PSMD13 antibody.
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ARG56225 anti-PSMD13 antibody WB image
Western blot: 35 µg of Y79 cell lysate stained with ARG56225 anti-PSMD13 antibody.
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ARG56225 anti-PSMD13 antibody FACS image
Flow Cytometry: 293 cells stained with ARG56225 anti-PSMD13 antibody (bottom histogram) or without primary antibody control (top histogram), followed by incubation with FITC labelled secondary antibody.
