ARG56253

anti-PSMB1 antibody

anti-PSMB1 antibody for ICC/IF,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes PSMB1
反应物种 Hu, Ms, Rat
应用 ICC/IF, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 PSMB1
抗原物种 Human
抗原 Recombinant protein of Human PSMB1
偶联标记 Un-conjugated
別名 Multicatalytic endopeptidase complex subunit C5; HC5; Proteasome component C5; PSC5; EC 3.4.25.1; Macropain subunit C5; Proteasome subunit beta type-1; PMSB1; Proteasome gamma chain

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 HepG2

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 19170 Mouse PSMB1

GeneID: 5689 Human PSMB1

GeneID: 94198 Rat PSMB1

基因名称 PSMB1
全名 proteasome (prosome, macropain) subunit, beta type, 1
背景介绍 The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq, Jul 2008]
生物功能 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. [UniProt]
预测分子量 26 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG56253 anti-PSMB1 antibody ICC/IF image

    Immunofluorescence: U2OS cells stained with ARG56253 anti-PSMB1 antibody.

  • ARG56253 anti-PSMB1 antibody WB image

    Western blot: HepG2 cell lysate stained with ARG56253 anti-PSMB1 antibody.