ARG40040
anti-PSMA6 antibody
anti-PSMA6 antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PSMA6 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PSMA6 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-246 of Human PSMA6 (NP_002782.1). |
| 偶联标记 | Un-conjugated |
| 別名 | Proteasome subunit alpha type-6; Proteasome iota chain; PROS27; EC 3.4.25.1; PROS-27; 27 kDa prosomal protein; p27K; IOTA; Macropain iota chain; Multicatalytic endopeptidase complex iota chain |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse skeletal muscle and MCF7 | ||||||
| 实际分子量 | 30 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PSMA6 |
| 全名 | proteasome subunit alpha 6 |
| 背景介绍 | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013] |
| 生物功能 | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. [UniProt] |
| 细胞定位 | Cytoplasm. Nucleus. Note=Colocalizes with TRIM5 in cytoplasmic bodies. [UniProt] |
| 预测分子量 | 27 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG40040 anti-PSMA6 antibody WB image
Western blot: 25 µg of Mouse skeletal muscle and MCF7 cell lysates stained with ARG40040 anti-PSMA6 antibody at 1:1000 dilution.
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ARG40040 anti-PSMA6 antibody WB image
Western blot: 25 µg of Mouse brain, PC-12 and A549 cell lysates stained with ARG40040 anti-PSMA6 antibody at 1:1000 dilution through one-step method.
