ARG45823
anti-PSMA3 antibody
anti-PSMA3 antibody for Flow cytometry,ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PSMA3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-Fr, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PSMA3 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to middle region of human PSMA3. |
| 偶联标记 | Un-conjugated |
| 別名 | PSMA3; proteasome (prosome, macropain) subunit, alpha type, 3; Proteasome subunit alpha type-3; Proteasome component C8; PSC3; HC8; Multicatalytic endopeptidase complex subunit C8; Macropain subunit C8; EC 3.4.25.1 |
应用说明
| 应用建议 |
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||||
| 实际分子量 | 28 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PSMA3 |
| 全名 | proteasome (prosome, macropain) subunit, alpha type, 3 |
| 背景介绍 | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| 生物功能 | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2. [UniProt] |
| 细胞定位 | Cytoplasm; Nucleus; Proteasome. [UniProt] |
| 预测分子量 | 28 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (7) Click the Picture to Zoom In
-
ARG45823 anti-PSMA3 antibody IHC-P image
Immunohistochemistry: Human intestinal cance stained with ARG45823 anti-PSMA3 antibody at 2 μg/ml dilution.
-
ARG45823 anti-PSMA3 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45823 anti-PSMA3 antibody at 2 μg/ml dilution.
-
ARG45823 anti-PSMA3 antibody WB image
Western blot: 293T stained with ARG45823 anti-PSMA3 antibody at 0.5 μg/ml dilution.
-
ARG45823 anti-PSMA3 antibody FACS image
Flow Cytometry: Hela stained with ARG45823 anti-PSMA3 antibody at 1 µg/10^6 cells dilution.
-
ARG45823 anti-PSMA3 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45823 anti-PSMA3 antibody at 2 μg/ml dilution.
-
ARG45823 anti-PSMA3 antibody WB image
Western blot: Rat testis stained with ARG45823 anti-PSMA3 antibody at 0.5 μg/ml dilution.
-
ARG45823 anti-PSMA3 antibody WB image
Western blot: Mouse lung stained with ARG45823 anti-PSMA3 antibody at 0.5 μg/ml dilution.
