概述

产品描述	Rabbit Polyclonal antibody recognizes PSMA1
反应物种	Hu, Ms, Rat
应用	ICC/IF, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	PSMA1
抗原物种	Human
抗原	Recombinant protein of Human PSMA1
偶联标记	Un-conjugated
別名	HC2; Proteasome subunit alpha type-1; Multicatalytic endopeptidase complex subunit C2; PROS30; Proteasome component C2; 30 kDa prosomal protein; PROS-30; EC 3.4.25.1; HEL-S-275; Proteasome nu chain; NU; Macropain subunit C2

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:50 - 1:200 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	U251

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 26440 Mouse PSMA1 GeneID: 29668 Rat PSMA1 GeneID: 5682 Human PSMA1 Swiss-port # P18420 Rat Proteasome subunit alpha type-1 Swiss-port # P25786 Human Proteasome subunit alpha type-1 Swiss-port # Q9R1P4 Mouse Proteasome subunit alpha type-1 More
基因名称	PSMA1
全名	proteasome (prosome, macropain) subunit, alpha type, 1
背景介绍	The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
生物功能	The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome (By similarity). Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells (By similarity). [UniProt]
预测分子量	30 kDa

检测图片 (1) Click the Picture to Zoom In