ARG67103

anti-PSIP1 / LEDGF antibody

anti-PSIP1 / LEDGF antibody for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Monkey

概述

产品描述 Mouse Monoclonal antibody recognizes PSIP1 / LEDGF
反应物种 Hu, Ms, Rat, Mk
应用 ELISA, ICC/IF, IHC-P, WB
宿主 Mouse
克隆 Monoclonal
靶点名称 PSIP1 / LEDGF
抗原物种 Human
抗原 Human PSIP1 / LEDGF recombinant fragment
偶联标记 Un-conjugated
別名 PSIP1; PC4 And SRSF1 Interacting Protein 1; LEDGF; DFS70; Lens Epithelium-Derived Growth Factor; PSIP2; P52; P75; PC4 And SFRS1 Interacting Protein 1; Dense Fine Speckles 70 KDa Protein; PC4 And SFRS1-Interacting Protein; CLL-Associated Antigen KW-7; PC4 And SFRS1 Interacting Protein 2; Transcriptional Coactivator P52/P75; Transcriptional Coactivator P75/P52; DFS 70; PAIP

应用说明

应用建议
应用 推荐稀释比
ELISA1:10000
ICC/IF1:200 - 1:1000
IHC-P1:200 - 1:1000
WB1:500-2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol and 0.5% BSA
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 101739 Mouse PSIP1

GeneID: 11168 Human PSIP1

GeneID: 313323 Rat PSIP1

基因名称 PSIP1
全名 PC4 And SRSF1 Interacting Protein 1
背景介绍 Enables DNA-binding transcription factor binding activity; chromatin binding activity; and transcription coactivator activity. Involved in mRNA 5'-splice site recognition and positive regulation of transcription by RNA polymerase II. Located in heterochromatin; nuclear periphery; and nucleoplasm.
生物功能 Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.
细胞定位 Nucleus
预测分子量 60 kDa
翻译后修饰 Citrullination; Isopeptide bond; Phosphoprotein; Ubl conjugation

检测图片 (7) Click the Picture to Zoom In

  • ARG67103 anti-PSIP1 / LEDGF antibody IHC-P image

    Immunohistochemistry: Human breast cancer stained with ARG67103 anti-PSIP1 / LEDGF antibody.

  • ARG67103 anti-PSIP1 / LEDGF antibody WB image

    Western blot: HepG2 and Jurkat stained with ARG67103 anti-PSIP1 / LEDGF antibody.

  • ARG67103 anti-PSIP1 / LEDGF antibody ICC/IF image

    Immunofluorescence: NIH/3T3 stained with ARG67103 anti-PSIP1 / LEDGF antibody.

  • ARG67103 anti-PSIP1 / LEDGF antibody IHC-P image

    Immunohistochemistry: Human ovarian cancer stained with ARG67103 anti-PSIP1 / LEDGF antibody.

  • ARG67103 anti-PSIP1 / LEDGF antibody WB image

    Western blot: PC-12 stained with ARG67103 anti-PSIP1 / LEDGF antibody.

  • ARG67103 anti-PSIP1 / LEDGF antibody WB image

    Western blot: NIH/3T3 stained with ARG67103 anti-PSIP1 / LEDGF antibody.

  • ARG67103 anti-PSIP1 / LEDGF antibody WB image

    Western blot: Cos7 stained with ARG67103 anti-PSIP1 / LEDGF antibody.