概述

产品描述	Rabbit Polyclonal antibody recognizes PSD95
反应物种	Hu, Ms, Rat
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	PSD95
抗原物种	Human
抗原	Synthetic peptide of Human PSD95 (Swiss: P78352)
偶联标记	Un-conjugated
別名	Postsynaptic density protein 95; SAP90; PSD-95; Synapse-associated protein 90; PSD95; SAP-90; Disks large homolog 4

应用说明

应用建议	应用 推荐稀释比 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	Mouse brain

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 13385 Mouse DLG4 GeneID: 1742 Human DLG4 GeneID: 29495 Rat DLG4 Swiss-port # P31016 Rat Disks large homolog 4 Swiss-port # P78352 Human Disks large homolog 4 Swiss-port # Q62108 Mouse Disks large homolog 4 More
基因名称	DLG4
全名	discs, large homolog 4 (Drosophila)
背景介绍	This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能	Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity). [UniProt]
产品亮点	Related products: PSD95 antibodies; Anti-Rabbit IgG secondary antibodies; Related news: Neuronal Development Marker
研究领域	Neuroscience antibody
预测分子量	80 kDa
翻译后修饰	Palmitoylation of isoform 1 is required for targeting to postsynaptic density.

检测图片 (1) Click the Picture to Zoom In