ARG52404
anti-PSD95 antibody
anti-PSD95 antibody for Western blot and Rat
Neuroscience antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PSD95 |
|---|---|
| 反应物种 | Rat |
| 预测物种 | Hu, Ms, Bov, NHuPrm, Zfsh |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PSD95 |
| 抗原物种 | Rat |
| 抗原 | Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | Postsynaptic density protein 95; SAP90; PSD-95; Synapse-associated protein 90; PSD95; SAP-90; Disks large homolog 4 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | Specific for ~95k PSD-95 protein. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DLG4 |
| 全名 | discs, large homolog 4 (Drosophila) |
| 背景介绍 | PSD-95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004). Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004). |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 80 kDa |
| 翻译后修饰 | Palmitoylation of isoform 1 is required for targeting to postsynaptic density. |
检测图片 (1) Click the Picture to Zoom In
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ARG52404 anti-PSD95 antibody WB image
Western blot: rat hippocampal (Hipp) lysate stained with ARG52404 anti-PSD-95 antibody showing specific immunolabeling of the ~95k PSD-95 protein.
