ARG43978
anti-PRPF8 antibody
anti-PRPF8 antibody for ELISA,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PRPF8 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ELISA, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PRPF8 |
| 抗原物种 | Human |
| 抗原 | Human PRPF8 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Pre-mRNA-processing-splicing factor 8 |
| 別名 | PRPF8; Pre-MRNA Processing Factor 8; PRPC8; SNRNP220; Pre-MRNA-Processing-Splicing Factor 8; 220 KDa U5 SnRNP-Specific Protein; Splicing Factor Prp8; PRP8 Homolog; HPrp8; Prp8; RP13; P220; U5 SnRNP-Specific Protein (220 KD), Ortholog Of S. Cerevisiae Prp8p; PRP8 Pre-MRNA Processing Factor 8 Homolog; Precursor MRNA Processing Protein; Apoptosis-Regulated Protein; HPRP8; PRP8 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q6P2Q9 Human Pre-mRNA-processing-splicing factor 8 Swiss-port # Q99PV0 Mouse Pre-mRNA-processing-splicing factor 8 |
|---|---|
| 基因名称 | PRPF8 |
| 全名 | Pre-MRNA Processing Factor 8 |
| 背景介绍 | Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. |
| 生物功能 | Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. |
| 细胞定位 | Nucleus, Spliceosome |
| 预测分子量 | 274 kDa |
| 翻译后修饰 | Acetylation, Methylation, Phosphoprotein |
检测图片 (2) Click the Picture to Zoom In
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ARG43978 anti-PRPF8 antibody WB image
Western blot: Hela and SH-SY5Y stained with ARG43978 anti-PRPF8 antibody at 0.5 μg/mL dilution.
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ARG43978 anti-PRPF8 antibody WB image
Western blot: NIH/3T3 stained with ARG43978 anti-PRPF8 antibody at 0.5 μg/mL dilution.
