ARG45776
anti-PRMT8 antibody
anti-PRMT8 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PRMT8 |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PRMT8 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human PRMT8. |
| 偶联标记 | Un-conjugated |
| 別名 | PRMT8; Protein Arginine Methyltransferase 8; HRMT1L3; HRMT1L4; Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-Like Protein 4; Protein Arginine N-Methyltransferase 8; HMT1 HnRNP Methyltransferase-Like 3 (S. Cerevisiae); HMT1 HnRNP Methyltransferase-Like 4 (S. Cerevisiae); Protein Arginine N-Methyltransferase 4; HMT1 HnRNP Methyltransferase-Like 3; Arginine Methyltransferase 8; EC 2.1.1.319; EC 2.1.1.77 47; EC 2.1.1 47 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 45 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.01% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9NR22 Human Protein arginine N-methyltransferase 8 |
|---|---|
| 基因名称 | PRMT8 |
| 全名 | Protein Arginine Methyltransferase 8 |
| 背景介绍 | Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM, Mar 2008] |
| 生物功能 | S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer. [UniProt] |
| 细胞定位 | Cell membrane; Membrane. [UniProt] |
| 预测分子量 | 45 kDa |
| 翻译后修饰 | Lipoprotein; Methylation; Myristate. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45776 anti-PRMT8 antibody IHC-P image
Immunohistochemistry: Human breast cancer stained with ARG45776 anti-PRMT8 antibody at 2 μg/ml dilution.
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ARG45776 anti-PRMT8 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45776 anti-PRMT8 antibody at 2 μg/ml dilution.
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ARG45776 anti-PRMT8 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45776 anti-PRMT8 antibody at 2 μg/ml dilution.
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ARG45776 anti-PRMT8 antibody WB image
Western blot: Rat brain stained with ARG45776 anti-PRMT8 antibody at 0.5 μg/ml dilution.
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ARG45776 anti-PRMT8 antibody WB image
Western blot: Mouse brain stained with ARG45776 anti-PRMT8 antibody at 0.5 μg/ml dilution.
