ARG45222
anti-PRMT3 antibody
anti-PRMT3 antibody for Flow cytometry,ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PRMT3 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PRMT3 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human PRMT3. |
| 偶联标记 | Un-conjugated |
| 別名 | PRMT3; Protein Arginine Methyltransferase 3; HRMT1L3; Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-Like Protein 3; Protein Arginine N-Methyltransferase 3; HMT1 HnRNP Methyltransferase-Like 3 (S. Cerevisiae); HMT1 HnRNP Methyltransferase-Like 3; EC 2.1.1.319; EC 2.1.1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 60-70 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O60678 Human Protein arginine N-methyltransferase 3 |
|---|---|
| 基因名称 | PRMT3 |
| 全名 | Protein Arginine Methyltransferase 3 |
| 背景介绍 | This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts on 40S ribosomal protein S2 (rpS2), which is its major in-vivo substrate, and is involved in the proper maturation of the 80S ribosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
| 生物功能 | Protein-arginine N-methyltransferase that catalyzes both the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, and therefore falls into the group of type I methyltransferases (Probable). May regulate retinoic acid synthesis and signaling by inhibiting ALDH1A1 retinal dehydrogenase activity. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 60 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45222 anti-PRMT3 antibody ICC/IF image
Immunofluorescence: Caco-2 stained with ARG45222 anti-PRMT3 antibody at 5 ug/ml dilution.
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ARG45222 anti-PRMT3 antibody WB image
Western blot: MCF-7, HepG2, and Hela stained with ARG45222 anti-PRMT3 antibody at 0.5 μg/ml dilution.
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ARG45222 anti-PRMT3 antibody FACS image
Flow Cytometry: K562 stained with ARG45222 anti-PRMT3 antibody at 1 µg/10^6 cells dilution.
