ARG43933
anti-PRMT1 antibody
anti-PRMT1 antibody for ELISA,Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PRMT1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ELISA, FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PRMT1 |
| 抗原物种 | Human |
| 抗原 | Human PRMT1 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Protein arginine N-methyltransferase 1 |
| 別名 | PRMT1; Protein Arginine Methyltransferase 1; HRMT1L2; HCP1; ANM1; HMT1 (HnRNP Methyltransferase, S. Cerevisiae)-Like 2; Histone-Arginine N-Methyltransferase PRMT1; Protein Arginine N-Methyltransferase 1; Interferon Receptor 1-Bound Protein 4; Highly Conserved Protein 1; IR1B4; Heterogeneous Nuclear Ribonucleoprotein Methyltransferase 1-Like 2; HMT1 HnRNP Methyltransferase-Like 2 (S. Cerevisiae); EC 2.1.1.319; EC 2.1.1.77; EC 2.1.1; HMT2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRMT1 |
| 全名 | Protein Arginine Methyltransferase 1 |
| 背景介绍 | This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. |
| 生物功能 | Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, FMR1, ILF3, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15, EWS, HABP4, SERBP1, RBM15, FOXO1, CHTOP and MAP3K5/ASK1. |
| 细胞定位 | Cytoplasm; Nucleus |
| 预测分子量 | 42 kDa |
| 翻译后修饰 | Acetylation; Isopeptide bond; Phosphoprotein; Ubl conjugation |
检测图片 (5) Click the Picture to Zoom In
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ARG43933 anti-PRMT1 antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG43933 anti-PRMT1 antibody at 5 μg/ml dilution.
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ARG43933 anti-PRMT1 antibody WB image
Western blot: HepG2, A549 and Hela stained with ARG43933 anti-PRMT1 antibody at 0.5 μg/mL dilution.
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ARG43933 anti-PRMT1 antibody FACS image
Flow Cytometry: U937 cells stained with ARG43933 anti-PRMT1 antibody (blue) at 1 μg/1x10^6 cells dilution.
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ARG43933 anti-PRMT1 antibody WB image
Western blot: RH35 stained with ARG43933 anti-PRMT1 antibody at 0.5 μg/mL dilution.
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ARG43933 anti-PRMT1 antibody WB image
Western blot: Neuro-2a stained with ARG43933 anti-PRMT1 antibody at 0.5 μg/mL dilution.
