ARG59201
anti-PREB antibody
anti-PREB antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PREB |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PREB |
| 抗原物种 | Human |
| 抗原 | Recombinant protein corresponding to K42-N236 of Human PREB. |
| 偶联标记 | Un-conjugated |
| 別名 | Prolactin regulatory element-binding protein; SEC12; Mammalian guanine nucleotide exchange factor mSec12 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9HCU5 Human Prolactin regulatory element-binding protein |
|---|---|
| 基因名称 | PREB |
| 全名 | prolactin regulatory element binding |
| 背景介绍 | This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand. [provided by RefSeq, Jul 2008] |
| 生物功能 | Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription (By similarity). Guanine nucleotide exchange factor that activates SARA2. Required for the formation of COPII transport vesicles from the ER. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus. Note=Concentrates at endoplasmic reticulum exit sites. [UniProt] |
| 预测分子量 | 45 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59201 anti-PREB antibody WB image
Western blot: 50 µg of samples under reducing conditions. HeLa, Human placenta and A549 whole cell lysates stained with ARG59201 anti-PREB antibody at 0.5 µg/ml, overnight at 4°C.
