ARG45176
anti-PRDM5 antibody
anti-PRDM5 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PRDM5 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PRDM5 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human PRDM5. |
| 偶联标记 | Un-conjugated |
| 別名 | PRDM5; PR domain containing 5; PR domain-containing protein 5; BCS2; PFM2; PR domain zinc finger protein 5; EC 2.1.1.- |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 75 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRDM5 |
| 全名 | PR domain containing 5 |
| 背景介绍 | The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. [provided by RefSeq, Jul 2008] |
| 生物功能 | Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May cause G2/M arrest and apoptosis in cancer cells. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 73 kDa |
检测图片 (8) Click the Picture to Zoom In
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ARG45176 anti-PRDM5 antibody IHC-P image
Immunohistochemistry: Human mammary cancer stained with ARG45176 anti-PRDM5 antibody at 1 μg/ml dilution.
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ARG45176 anti-PRDM5 antibody ICC/IF image
Immunofluorescence: U20S stained with ARG45176 anti-PRDM5 antibody at 2 ug/ml dilution.
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ARG45176 anti-PRDM5 antibody WB image
Western blot: HL-60 stained with ARG45176 anti-PRDM5 antibody at 0.25 μg/ml dilution.
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ARG45176 anti-PRDM5 antibody FACS image
Flow Cytometry: CACO-2 stained with ARG45176 anti-PRDM5 antibody at 1 µg/10^6 cells dilution.
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ARG45176 anti-PRDM5 antibody IHC-P image
Immunohistochemistry: Rat Intestinal lymph node stained with ARG45176 anti-PRDM5 antibody at 1 μg/ml dilution.
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ARG45176 anti-PRDM5 antibody WB image
Western blot: Rat ovary stained with ARG45176 anti-PRDM5 antibody at 0.25 μg/ml dilution.
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ARG45176 anti-PRDM5 antibody IHC-P image
Immunohistochemistry: Mouse intestine stained with ARG45176 anti-PRDM5 antibody at 1 μg/ml dilution.
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ARG45176 anti-PRDM5 antibody WB image
Western blot: Mouse ovary stained with ARG45176 anti-PRDM5 antibody at 0.25 μg/ml dilution.
