ARG51451
anti-PRDM1 / Blimp 1 antibody
anti-PRDM1 / Blimp 1 antibody for Western blot and Human,Mouse,Rat
Gene Regulation antibody; Immune System antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PRDM1 / Blimp 1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PRDM1 / Blimp 1 |
| 抗原物种 | Human |
| 抗原 | Peptide sequence around aa.124~128(D-T-V-P-K) derived from Human PRDM1 / Blimp1. |
| 偶联标记 | Un-conjugated |
| 別名 | Beta-interferon gene positive regulatory domain I-binding factor; PR domain zinc finger protein 1; BLIMP-1; BLIMP1; PRDI-binding factor 1; PR domain-containing protein 1; EC 2.1.1.-; PRDI-BF1; Positive regulatory domain I-binding factor 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antibodies were produced by immunizing rabbits with KLH-conjugated synthetic peptide. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| 缓冲液 | PBS (without Mg2+ and Ca2+, pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRDM1 |
| 全名 | PR domain containing 1, with ZNF domain |
| 背景介绍 | Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. |
| 生物功能 | Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569). [UniProt] |
| 研究领域 | Gene Regulation antibody; Immune System antibody |
| 预测分子量 | 92 kDa |
| 翻译后修饰 | Sumoylation at Lys-816 by PIAS1 augments transcriptional repressor activity, and is critical for plasma cell differentiation. Ubiquitinated by the SCF(FBXO11) complex, leading to its degradation by the proteasome. |
检测图片 (1) Click the Picture to Zoom In
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ARG51451 anti-PRDM1 / Blimp 1 antibody WB image
Western blot: 20 µg of HeLa cell lysates stained with ARG51451 anti-PRDM1 / Blimp 1 antibody at 1:500 dilution.
