ARG43972
anti-PRAM1 antibody
anti-PRAM1 antibody for ELISA,Flow cytometry,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PRAM1 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PRAM1 |
| 抗原物种 | Human |
| 抗原 | Human PRAM1 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | PML-RARA-regulated adapter molecule 1 |
| 別名 | PRAM1; PML-RARA Regulated Adaptor Molecule 1; PML-RAR; PML-RARA-Regulated Adapter Molecule 1; PRAM-1; PRAM; PML-RARA Target Gene Encoding An Adaptor Molecule-1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q96QH2 Human PML-RARA-regulated adapter molecule 1 |
|---|---|
| 基因名称 | PRAM1 |
| 全名 | PML-RARA Regulated Adaptor Molecule 1 |
| 背景介绍 | The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha). |
| 生物功能 | May be involved in myeloid differentiation. May be involved in integrin signaling in neutrophils. Binds to PtdIns4P. |
| 预测分子量 | 74 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (2) Click the Picture to Zoom In
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ARG43972 anti-PRAM1 antibody WB image
Western blot: THP-1 stained withARG43972 anti-PRAM1 antibody at 0.5 μg/mL dilution.
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ARG43972 anti-PRAM1 antibody FACS image
Flow Cytometry: JK cells stained with ARG43972 anti-PRAM1 antibody (blue) at 1 μg/1x10^6 cells dilution.
