ARG45805
anti-PRAGMIN / SGK223 antibody
anti-PRAGMIN / SGK223 antibody for Flow cytometry,ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PRAGMIN / SGK223 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PRAGMIN / SGK223 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human PRAGMIN / SGK223. |
| 偶联标记 | Un-conjugated |
| 別名 | PRAG1; PEAK1 Related, Kinase-Activating Pseudokinase 1; SgK223; Sugen Kinase 223; PRAGMIN; PEAK2; NACK; Inactive Tyrosine-Protein Kinase PRAG1; Pragmin, RND2 Effector Protein; PEAK Family Member 2; DKFZp761P0423; PEAK1-Related Kinase-Activating Pseudokinase 1; Tyrosine-Protein Kinase SgK223; Homolog Of Rat Pragma Of Rnd2; Tyrosine-Protein Kinase PRAG1; Pragmin; SGK223 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 200 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRAG1 |
| 全名 | PEAK1 Related, Kinase-Activating Pseudokinase 1 |
| 背景介绍 | This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA). [provided by RefSeq, Mar 2014] |
| 生物功能 | Catalytically inactive protein kinase that acts as a scaffold protein. Functions as an effector of the small GTPase RND2, which stimulates RhoA activity and inhibits NGF-induced neurite outgrowth (By similarity). Promotes Src family kinase (SFK) signaling by regulating the subcellular localization of CSK, a negative regulator of these kinases, leading to the regulation of cell morphology and motility by a CSK-dependent mechanism (By similarity). Acts as a critical coactivator of Notch signaling (By similarity). [UniProt] |
| 细胞定位 | Cell junction; Cytoplasm; Nucleus. [UniProt] |
| 预测分子量 | 150 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45805 anti-PRAGMIN / SGK223 antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45805 anti-PRAGMIN / SGK223 antibody at 5 μg/ml dilution.
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ARG45805 anti-PRAGMIN / SGK223 antibody WB image
Western blot: A549 stained with ARG45805 anti-PRAGMIN / SGK223 antibody at 0.5 μg/ml dilution.
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ARG45805 anti-PRAGMIN / SGK223 antibody FACS image
Flow Cytometry: HepG2 stained with ARG45805 anti-PRAGMIN / SGK223 antibody at 1 µg/10^6 cells dilution.
