ARG41189
anti-PPP4R1 antibody
anti-PPP4R1 antibody for Immunoprecipitation,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PPP4R1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PPP4R1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 324-647 of Human PPP4R1 (NP_001035847.1). |
| 偶联标记 | Un-conjugated |
| 別名 | Serine/threonine-protein phosphatase 4 regulatory subunit 1; PP4R1; MEG1; PP4(Rmeg) |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | SKOV3 | ||||||
| 实际分子量 | 130 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8K2V1 Mouse Serine/threonine-protein phosphatase 4 regulatory subunit 1 Swiss-port # Q8TF05 Human Serine/threonine-protein phosphatase 4 regulatory subunit 1 |
|---|---|
| 基因名称 | PPP4R1 |
| 全名 | protein phosphatase 4, regulatory subunit 1 |
| 背景介绍 | This gene encodes one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] |
| 生物功能 | Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. [UniProt] |
| 预测分子量 | 107 kDa |
检测图片 (2) Click the Picture to Zoom In
-
ARG41189 anti-PPP4R1 antibody WB image
Western blot: 25 µg of SKOV3 cell lysate stained with ARG41189 anti-PPP4R1 antibody at 1:1000 dilution.
-
ARG41189 anti-PPP4R1 antibody IP image
Immunoprecipitation: 200 µg extracts of 293T cells were immunoprecipitated and stained with ARG41189 anti-PPP4R1 antibody at 1:1000 dilution.
