ARG43956
anti-PPP1R11 antibody
anti-PPP1R11 antibody for ELISA,Flow cytometry,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PPP1R11 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ELISA, FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PPP1R11 |
| 抗原物种 | Human |
| 抗原 | Human PPP1R11 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | E3 ubiquitin-protein ligase PPP1R11 |
| 別名 | PPP1R11; Protein Phosphatase 1 Regulatory Inhibitor Subunit 11; HCGV; CFAP255; HCG-V; TCTE5; Protein Phosphatase 1 Regulatory Subunit 11; Hemochromatosis Candidate Gene V Protein; E3 Ubiquitin-Protein Ligase PPP1R11; Protein Phosphatase Inhibitor 3; Tctex5; HCG V; Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 11; T-Complex-Associated-Testis-Expressed 5; Inhibitor-3; EC 2.3.2.27; TCTEX5; IPP3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PPP1R11 |
| 全名 | Protein Phosphatase 1 Regulatory Inhibitor Subunit 11 |
| 背景介绍 | This gene encodes a specific inhibitor of protein phosphatase-1 (PP1) with a differential sensitivity toward the metal-independent and metal-dependent forms of PP1. The gene is located within the major histocompatibility complex class I region on chromosome 6. |
| 生物功能 | Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. |
| 细胞定位 | Cytoplasm, Nucleus |
| 预测分子量 | 14 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein, Ubl conjugation |
检测图片 (4) Click the Picture to Zoom In
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ARG43956 anti-PPP1R11 antibody WB image
Western blot: HepG2 and HeLa stained with ARG43956 anti-PPP1R11 antibody at 0.5 μg/mL dilution.
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ARG43956 anti-PPP1R11 antibody FACS image
Flow Cytometry: MCF-7 cells stained with ARG43956 anti-PPP1R11 antibody (blue) at 1 μg/1x10^6 cells dilution.
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ARG43956 anti-PPP1R11 antibody WB image
Western blot: Rat testis and Rat liver stained with ARG43956 anti-PPP1R11 antibody at 0.5 μg/mL dilution.
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ARG43956 anti-PPP1R11 antibody WB image
Western blot: Mouse testis stained with ARG43956 anti-PPP1R11 antibody at 0.5 μg/mL dilution.
