ARG45590
anti-PPM1E antibody
anti-PPM1E antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PPM1E |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PPM1E |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human PPM1E. |
| 偶联标记 | Un-conjugated |
| 別名 | PPM1E; Protein Phosphatase, Mg2+/Mn2+ Dependent 1E; CaMKP-N; POPX1; Partner Of PIX 1; KIAA1072; PP2CH; Ca(2+)/Calmodulin-Dependent Protein Kinase Phosphatase N; Nuclear Calmodulin-Dependent Protein Kinase Phosphatase; Protein Phosphatase 1E (PP2C Domain Containing); Protein Phosphatase 1E; Partner Of PIX-Alpha; Partner Of PIXA; CaMKP-Nucleus; CaMKN; Protein Phosphatase, Mg2+/Mn2+ Dependent, 1E; EC 3.1.3.16; CAMKPN; CAMKN |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 84 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PPM1E |
| 全名 | Protein Phosphatase, Mg2+/Mn2+ Dependent 1E |
| 背景介绍 | This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012] |
| 生物功能 | Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2 (By similarity). Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2. [UniProt] |
| 细胞定位 | Cytoplasm; Nucleus. [UniProt] |
| 预测分子量 | 84 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45590 anti-PPM1E antibody IHC-P image
Immunohistochemistry: Human melanoma stained with ARG45590 anti-PPM1E antibody at 1 μg/ml dilution.
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ARG45590 anti-PPM1E antibody ICC/IF image
Immunofluorescence: A431 stained with ARG45590 anti-PPM1E antibody at 2 μg/ml dilution.
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ARG45590 anti-PPM1E antibody WB image
Western blot: U2OS stained with ARG45590 anti-PPM1E antibody at 0.5 μg/ml dilution.
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ARG45590 anti-PPM1E antibody FACS image
Flow Cytometry: K562 stained with ARG45590 anti-PPM1E antibody at 1 µg/10^6 cells dilution.
