ARG57492
anti-PPIE antibody [17E8]
anti-PPIE antibody [17E8] for Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [17E8] recognizes PPIE |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 17E8 |
| 同位型 | IgG1, kappa |
| 靶点名称 | PPIE |
| 抗原物种 | Human |
| 抗原 | Recombinant Human PPIE (aa. 1-301aa) purified from E. coli. |
| 偶联标记 | Un-conjugated |
| 別名 | Cyclophilin-33; CYP-33; Cyclophilin E; PPIase E; EC 5.2.1.8; Peptidyl-prolyl cis-trans isomerase E; CYP33; Rotamase E |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9UNP9 Human Peptidyl-prolyl cis-trans isomerase E |
|---|---|
| 基因名称 | PPIE |
| 全名 | peptidylprolyl isomerase E (cyclophilin E) |
| 背景介绍 | The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified. [provided by RefSeq, Aug 2010] |
| 生物功能 | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Combines RNA-binding and PPIase activities. May be involved in muscle- and brain-specific processes. May be involved in pre-mRNA splicing. [UniProt] |
| 预测分子量 | 33 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG57492 anti-PPIE antibody [17E8] WB image
Western blot: 40 µg of HeLa, Jurkat, 293T, A549, K562, MCF7 and LnCap cell lysates stained with ARG57492 anti-PPIE antibody [17E8] at 1:1000 dilution.
