ARG45215
anti-PPFIA1 antibody
anti-PPFIA1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PPFIA1 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PPFIA1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human PPFIA1. |
| 偶联标记 | Un-conjugated |
| 別名 | PPFIA1; PTPRF Interacting Protein Alpha 1; LIPRIN; LIP.1; Protein Tyrosine Phosphatase, Receptor Type, F Polypeptide (PTPRF), Interacting Protein (Liprin), Alpha 1; Protein Tyrosine Phosphatase Receptor Type F Polypeptide-Interacting Protein Alpha-1; LAR-Interacting Protein 1; Liprin-Alpha-1; Liprin-Alpha1; LIP-1; LIP1; PTPRF-Interacting Protein Alpha-1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 160 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PPFIA1 |
| 全名 | PTPRF Interacting Protein Alpha 1 |
| 背景介绍 | The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
| 生物功能 | May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 135 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45215 anti-PPFIA1 antibody IHC-P image
Immunohistochemistry: Human gastric signet ring cell carcinoma stained with ARG45215 anti-PPFIA1 antibody at 2 μg/ml dilution.
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ARG45215 anti-PPFIA1 antibody ICC/IF image
Immunofluorescence: A431 stained with ARG45215 anti-PPFIA1 antibody at 5 ug/ml dilution.
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ARG45215 anti-PPFIA1 antibody WB image
Western blot: Hela, 293T, and MCF-7 stained with ARG45215 anti-PPFIA1 antibody at 0.5 μg/ml dilution.
