ARG45221
anti-PP11 antibody
anti-PP11 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PP11 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PP11 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human ENDOU. |
| 偶联标记 | Un-conjugated |
| 別名 | ENDOU; Endonuclease, Poly(U) Specific; PP11; PRSS26; P11; Uridylate-Specific Endoribonuclease; Endonuclease, PolyU-Specific; Placental Protein 11; Protein EndoU; Poly(U)-Specific Endoribonuclease; 22 Serine Protease; 26 Serine Protease; EC 4.6.1.- |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 47 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ENDOU |
| 全名 | Endonuclease, Poly(U) Specific |
| 背景介绍 | This gene encodes a protein with endoribonuclease activity that binds polyuridine-enriched single-stranded RNA. This gene was initially characterized based on its high expression in placenta but was mischaracterized as a serine protease. In mouse, this gene promotes tolerance to self-antigens by regulating B cell activation-induced cell death (AICD). The protein may be useful as a tumor marker. Multiple alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2020] |
| 生物功能 | Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end. The UU and GU sites are more efficiently cleaved than CU and AU sites. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 47 kDa |
| 翻译后修饰 | Disulfide bond. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45221 anti-PP11 antibody IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG45221 anti-PP11 antibody at 2 μg/ml dilution.
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ARG45221 anti-PP11 antibody ICC/IF image
Immunofluorescence: Caco-2 stained with ARG45221 anti-PP11 antibody at 5 ug/ml dilution.
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ARG45221 anti-PP11 antibody WB image
Western blot: Human placenta tissue stained with ARG45221 anti-PP11 antibody at 0.5 μg/ml dilution.
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ARG45221 anti-PP11 antibody FACS image
Flow Cytometry: U87 stained with ARG45221 anti-PP11 antibody at 1 µg/10^6 cells dilution.
