ARG44894
anti-POU3F1 / OCT6 antibody
anti-POU3F1 / OCT6 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse,Rat
概述
| 产品描述 | Mouse Monoclonal antibody recognizes POU3F1 / OCT6 |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | POU3F1 / OCT6 |
| 抗原物种 | Mouse |
| 偶联标记 | Un-conjugated |
| 別名 | POU3F1; POU Class 3 Homeobox 1; OCT6; SCIP; OTF6; POU Domain, Class 3, Transcription Factor 1; Octamer-Binding Transcription Factor 6; POU Domain Transcription Factor SCIP; Octamer-Binding Protein 6; OTF-6; POU Domain Class 3, Transcription Factor 1; Oct-6 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purified. |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P20267 Rat POU domain, class 3, transcription factor 1 Swiss-port # P21952 Mouse POU domain, class 3, transcription factor 1 |
|---|---|
| 基因名称 | POU3F1 |
| 全名 | POU Class 3 Homeobox 1 |
| 背景介绍 | Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of gene expression; and positive regulation of transcription, DNA-templated. Predicted to act upstream of or within keratinocyte differentiation; nervous system development; and positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] |
| 生物功能 | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters. Acts as a transcriptional repressor of myelin-specific genes. [Uniprot] |
| 细胞定位 | Nucleus. [Uniprot] |
| 预测分子量 | 45 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG44894 anti-POU3F1 / OCT6 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG44894 anti-POU3F1 / OCT6 antibody at 5 µg/mL dilution.
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ARG44894 anti-POU3F1 / OCT6 antibody WB image
Western blot: Rat brain stained with ARG44894 anti-POU3F1 / OCT6 antibody at 1 µg/mL dilution.
