ARG66454
anti-POLR2I / RPB8 antibody
anti-POLR2I / RPB8 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes POLR2I / RPB8 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Bov, Chk, Dog, Mk, Pig, Rb |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | POLR2I / RPB8 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide within the center region of Human POLR2I / RPB8. |
| 偶联标记 | Un-conjugated |
| 別名 | RPB9; RPB14.5; hRPB14.5; DNA-directed RNA polymerase II subunit I; DNA-directed RNA polymerase II subunit RPB9; RNA polymerase II subunit B9; RNA polymerase II 14.5 kDa subunit |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 30% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P36954 Human DNA-directed RNA polymerase II subunit RPB9 Swiss-port # P60898 Mouse DNA-directed RNA polymerase II subunit RPB9 |
|---|---|
| 基因名称 | POLR2I |
| 全名 | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa |
| 背景介绍 | This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. [provided by RefSeq, Jul 2008] |
| 生物功能 | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template (By similarity). [UniProt] |
| 细胞定位 | Nucleus, nucleolus. [UniProt] |
| 预测分子量 | 15 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66454 anti-POLR2I / RPB8 antibody WB image
Western blot: A549, NIH/3T3 and PC12 whole cell lysates stained with ARG66454 anti-POLR2I / RPB8 antibody.
