ARG41222
anti-POLR1C antibody
anti-POLR1C antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes POLR1C |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | POLR1C |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 319-346 of Human POLR1C. |
| 偶联标记 | Un-conjugated |
| 別名 | RPC40; RPA39; DNA-directed RNA polymerase I subunit C; RPA5; RNA polymerases I and III subunit AC1; DNA-directed RNA polymerases I and III subunit RPAC1; AC40; RPA40; RPAC1; DNA-directed RNA polymerases I and III 40 kDa polypeptide; TCS3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HeLa | ||||||
| 实际分子量 | ~ 40 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O15160 Human DNA-directed RNA polymerases I and III subunit RPAC1 Swiss-port # P52432 Mouse DNA-directed RNA polymerases I and III subunit RPAC1 |
|---|---|
| 基因名称 | POLR1C |
| 全名 | polymerase (RNA) I polypeptide C, 30kDa |
| 背景介绍 | The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Defects in this gene have been associated with Treacher Collins syndrome (TCS). [provided by RefSeq, Mar 2011] |
| 生物功能 | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity). [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 39 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG41222 anti-POLR1C antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human hepatocarcinoma tissue stained with ARG41222 anti-POLR1C antibody.
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ARG41222 anti-POLR1C antibody WB image
Western blot: 20 ug of HeLa whole cell lysate stained with ARG41222 anti-POLR1C antibody at 1:2000 dilution.
