ARG45760
anti-PNP / Purine nucleoside phosphorylase antibody [7G5]
anti-PNP / Purine nucleoside phosphorylase antibody [7G5] for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [7G5] recognizes PNP / Purine nucleoside phosphorylase |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 7G5 |
| 同位型 | IgG2b |
| 靶点名称 | PNP / Purine nucleoside phosphorylase |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to middle region of human PNP / Purine nucleoside phosphorylase. |
| 偶联标记 | Un-conjugated |
| 別名 | EC 2.4.2.1; Purine nucleoside phosphorylase; Inosine-guanosine phosphorylase; PNP; PRO1837; Inosine phosphorylase; PUNP; NP |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 32 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PNP |
| 全名 | purine nucleoside phosphorylase |
| 背景介绍 | This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008] |
| 生物功能 | The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. [UniProt] |
| 细胞定位 | Cytoplasm; Cytoskeleton; Cytoplasm. [UniProt] |
| 预测分子量 | 32 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45760 anti-PNP / Purine nucleoside phosphorylase antibody [7G5] IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG45760 anti-PNP / Purine nucleoside phosphorylase antibody [7G5] at 2 μg/ml dilution.
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ARG45760 anti-PNP / Purine nucleoside phosphorylase antibody [7G5] ICC/IF image
Immunofluorescence: A431 stained with ARG45760 anti-PNP / Purine nucleoside phosphorylase antibody [7G5] at 5 μg/ml dilution.
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ARG45760 anti-PNP / Purine nucleoside phosphorylase antibody [7G5] WB image
Western blot: A549 stained with ARG45760 anti-PNP / Purine nucleoside phosphorylase antibody [7G5] at 0.5 μg/ml dilution.
